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Turkish Journal of Chemistry

Synthesis of new substituted 2,2-bis-(3,5-di-t-butyl-4-hydroxybenzyl)benzocycloalkanones, bromopropiophenones, and their alcohol analogs

Jabbar KHALAFY1, Mehdi RIMAZ1, Sara TAGHINEJHAD1,2,
Mirzagha BABAZADEH2
1Chemistry Department, Urmia University, P. O. Box 57154, Urmia-IRAN
e-mails: j.khalafi@mail.urmia.ac.ir, jkhalafi@yahoo.com
2Department of Chemistry, Faculty of Science, Tabriz Branch,
Islamic Azad University, Tabriz-IRAN

Abstract: A new series of substituted 2,2-bis-(3,5-di-t-butyl-4-hydroxybenzyl) benzocycloalkanones, bromopropiophenones, and their alcohol analogs were synthesized. The corresponding alcohols may act as potential allosteric modulators of GABAB receptors.

Key Words: Benzocycloalkanone, allosteric modulator, GABAB receptor, propiophenone

Turk. J. Chem., 35, (2011), 543-552.
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Other articles published in the same issue: Turk. J. Chem.,vol.35,iss.4.