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Turkish Journal of Chemistry

Synthesis and characterization of novel benzovesamicol analogs

Thaer ASSAAD
Atomic Energy Commission (AEC), Damascus,
P. O. Box 6091, SYRIAN ARAB REPUBLIC
e-mail: cscientific@aec.org.sy

Abstract: Three new racemic vesamicol analogs were successfully prepared in good yields and high purity. All compounds were characterized by both IR and NMR spectroscopy. Compounds (\pm)-5 and (\pm)-6 showed a moderate lipophilicity compared with reference compounds IBVM and DRC140, respectively. However, the lipophilicity of DRC140 and (\pm)-9 showed very similar behaviors.

Key Words: Benzovesamicol, ethylenedicysteine, vesicular acetylcholine transporter


Turk. J. Chem., 35, (2011), 189-200.
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Other articles published in the same issue: Turk. J. Chem.,vol.35,iss.2.