Turkish Journal of Chemistry

Chemical composition and antimicrobial activity of the essential oils of Geranium columbinum L. and G. lucidum L. (Geraniaceae)
Niko RADULOVIC¹, Milan DEKIC^1,2, Zorica STOJANOVIC RADIC³, Radosav PALIC¹
¹Department of Chemistry, Faculty of Science and Mathematics, University of Nis,
Visegradska 33, 18000 Nis-SERBIA
e-mail: vangelis0703@yahoo.com
²Department of Biochemical and Medical Sciences State, University of Novi Pazar,
Vuka Karadzica bb, 36300 Novi Pazar-SERBIA
³Department of Biology and Ecology, Faculty of Science and Mathematics, University of Nis,
Visegradska 33, 18000 Nis-SERBIA

Abstract: The chemistry of Geranium columbinum and G. lucidum volatiles has been studied here for the first time. The essential oils were obtained by hydrodistillation, analyzed by GC and GC-MS, and screened for their in vitro antibacterial and antifungal activity in a microdilution assay. In total, 172 constituents were identified, accounting for 88.1%-96.7% of the detected GC peak areas. The essential oils consisted mainly of fatty acids and fatty acid-derived compounds (65.0%-86.3%). The major compounds of the essential oils were hexadecanoic acid, hexahydrofarnesyl acetone, and tetracosane. The antimicrobial assay showed a strong activity of the oil from aerial parts of G. columbinum against the pathogenic yeast C. albicans (MIC = 0.437, MBC = 1.75 mg/mL).

Key Words: Geranium columbinum, Geranium lucidum, Geraniaceae, essential oil composition, hexadecanoic acid, hexahydrofarnesyl acetone, tetracosane, antimicrobial activity

Turk. J. Chem., 35, (2011), 499-512.
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Other articles published in the same issue: Turk. J. Chem.,vol.35,iss.3.