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Turkish Journal of Chemistry

Methoxyflavonoids from Pinaropappus roseus

Ü. Şebnem HARPUT, İclal SARACOĞLU1, Yukio OGIHARA2,3
1Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy,
06100 Ankara-TURKEY
e-mail: shorput@hacettepe.edu.tr
2Nagoya City University, Graduate School of Pharmaceutical Sciences, Tanabe-dori 3-1,
Mizuho-ku, Nagoya 467-8603, JAPAN
3Meijo University, Faculty of Pharmacy, 150 Yagotoyama,
Tenpaku-ku, Nagoya 468-8503, JAPAN

Abstract: Three rare methoxyflavonoids, rhamnazin 3-O-rutinoside (1), rhamnocitrin 3-O-rutinoside (2) and isorhamnetin 3-O-rutinoside (3), were isolated from the methanolic extract of Pinaropappus roseus together with 2 well-known flavonoids, quercetin 3-O-rutinoside (=rutin) (4) and kaempferol 3-O-rutinoside (5). The structures of the isolated compounds were elucidated on the basis of UV, 1D and 2D NMR and FAB-Mass spectral analysis. Free radical scavenging activities of the isolated compounds were also demonstrated. This is the first report on the chemical composition of the genus Pinaropappus.

Key Words: Pinaropappus roseus, Asteraceae, rhamnazin 3-O-rutinoside, rhamnocitrin 3-O- rutinoside, isorhamnetin 3-O-rutinoside, flavonoids


Turk. J. Chem., 28, (2004), 761-766.
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Other articles published in the same issue: Turk. J. Chem.,vol.28,iss.6.