Turkish Journal of Biology

Abstract: The introduction of foreign genetic material into mouse genomes by microinjection is an important tool in studying the properties and effects of many genes in vivo. Transgenic mouse technology enables the study of gene regulation, embryology and development. The objective of this research was the optimization of transgenic manipulation in the laboratory, by the production of model mice harbouring human growth hormone, and thwe identification of the transgenic mice.

Key Words: Transgenic mice, human growth hormone, microinjection